The original data formats are all converted to the native PathVisio pathway model language (GPML), which is subsequently converted to a semantic model (RDF). Three different queries are executed to retrieve the metabolic reaction data from the RDF data.

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The data cleanup consisted out of merging metabolic reactions based on the combination of unique Wikidata identifiers for the source and target metabolites, for each reaction. Alos, a unique reaction ID was added for each unique source-target combination.